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Prof Chanito talking about Carbamazepine 1. It works by blocking Sodium Channels 2. It is the Drug of Choice for Trigeminal Neuralgia 3. It can be used in Mania and Diabetes Insipidus 4. It can induce its own metabolism and CYP-450 enzymes accelerating metabolism of other drugs 5.Bone marrow suppression is a rare but fatal ADR 6. Common ADRs: Dizziness, Drowsiness, Ataxia, N&V😂 7. Key interactions: Induces CYP-3A4 and thus metabolism of other drugs, Carbamazepine MAOIs or TCAs (esp Imipramine a
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