Statins are not only cholesterol-lowering medications; they also have anti-inflammatory effects. They can reduce hs-CRP, improve endothelial function, decrease oxidative stress, and help stabilize atherosclerotic plaques. While their primary cardiovascular benefit comes from lowering ApoB-containing lipoproteins (LDL cholesterol), these additional effects may contribute to their overall risk reduction. Some statins are more lipophilic and can cross the blood-brain barrier to a greater degree, wh
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Statins are not only cholesterol-lowering medications; they also have anti-inflammatory effects. They can reduce hs-CRP, improve endothelial function, decrease oxidative stress, and help stabilize atherosclerotic plaques. While their primary cardiovascular benefit comes from lowering ApoB-containing lipoproteins (LDL cholesterol), these additional effects may contribute to their overall risk reduction. Some statins are more lipophilic and can cross the blood-brain barrier to a greater degree, wh
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Do statins cause sarcopenia? Loss of muscle? Diabetes? Dementia? In fact, in the largest data sets, statins not only don't cause these issues, but actually improve them. Statins have shown a 22% reduction in dementia and a 32% reduction in Alzheimer's. In 3% of pre-diabetic or diabetic patients, statins can cause a 0.1% increase in A1c versus a 50% reduction in cardiovascular events. In the latest study looking at 20 million person years of follow up, there were no muscle related symptoms. Anyon
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