The transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell …

Mar 22, 2024 · In this review, we focus on the mechanism, physiology, pathology, as well as therapeutics of TGF-β signaling, aiming to provide historical, current, and future perspectives …

Dec 22, 2022 · The transforming growth factor beta (TGF-β) is a crucial cytokine that get increasing concern in recent years to treat human diseases. This signal controls multiple …

Apr 11, 2015 · Discover the TGF Beta signaling pathway and impact on cell growth & tissue homeostasis. Learn here the mechanisms behind this vital signaling cascade.

Jun 1, 2023 · Given the importance of TGFβ signaling in a range of human diseases, academic laboratories and pharmaceutical companies around the world have developed various TGFβ …

The basic TGF-β signaling system consists of two receptor serine/threonine protein kinases (receptor types I and II) and a family of direct receptor substrates (SMADs) that move into the …

Sep 14, 2023 · Here, we review how TGF-β coordinates multicellular response programs in health and disease and how this knowledge can be leveraged to develop treatments for diseases of …

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three [1] different mammalian isoforms …

Aug 1, 2025 · Uncover the TGFβ pathway, a fundamental biological regulator crucial for cellular balance. Learn how its intricate control impacts both well-being and illness.

Sep 14, 2023 · Here, we review how TGF-β coordinates multicellular response programs in health and disease and how this knowledge can be leveraged to develop treatments for diseases of …