We will review the mechanisms of resistance and triggers resulting in AmpC expression, the species-specific epidemiology of AmpC production, approaches to the detection of AmpC …

Aug 7, 2024 · In this guidance document, such organisms are described as having a moderate risk for clinically significant AmpC production. Resistance due to ampC induction can be …

Explore the structure, regulation, and clinical impact of AmpC beta-lactamases, including detection methods and potential inhibitors.

Sep 21, 2024 · AmpC enzymes are a class of beta-lactamases produced by Gram-negative bacteria, including several Enterobacterales. When produced in sufficient amounts, AmpCs …

Jul 7, 2025 · Chromosomal AmpC enzymes (which can also be called inducible AmpC enzymes) and plasmid-borne AmpC enzymes are the two main types of AmpC beta-lactamases that …

Organisms such as H. alvei, Citrobacter youngae, and Yersinia enterocolitica carry chromosomal AmpC genes but are not reported in many clinical reports, limiting the ability to interpret the …

Take-Away Points Antimicrobial resistance is a growing concern, especially with Gram-negative organisms. AmpC is an inducible resistance mechanism with the highest concern in HECK …

The AmpC β-lactamase confers resistance to penicillins and most β-lactamase inhibitor combinations, 1st – 3rd generation cephalosporins, ceftaroline, and aztreonam.

AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae and a few other organisms, where they mediate resistance to …

Introduction –What are AmpC B-Lactamases? AmpC production generally occurs by one of three mechanisms: Inducible chromosomal resistance Non-inducible chromosomal de-repression …