The Arizona Cardinals and San Francisco 49ers made game designations today.

San Francisco 49ers defensive line has been ravaged by injuries, leaving a dramatically different group preparing to start in ...

One 49ers insider projected the starting line Sunday would be defensive ends Keion White and Khalid Kareem, and defensive ...

San Francisco's play-action attack ranks among the NFL's best, while Arizona's sits near the bottom — making deception a ...

An update on five-time Pro Bowl defensive end Nick Bosa revealed the severity of an injury he suffered at the 49ers' practice ...

John Lynch said that the team and Brandin Cooks had been communicating for years before he signed with the 49ers.

Over the last couple of years, the San Francisco 49ers have had extremely bad luck on the injury front. Through the first two ...

San Francisco 49ers star pass rusher Nick Bosa injured his calf warming up for practice earlier this week and will miss a few ...

SANTA CLARA — What was that Mike Tomlin said a week or so ago? The Browns are gonna Browns? Well, along the same lines, the ...

The San Francisco 49ers have barely had time to enjoy their 2-0 start before another injury hits their defensive front. After ...

The San Francisco 49ers' Week 3 matchup vs. the Arizona Cardinals won't be easy with San Francisco's injury report looking ...

Arizona Cardinals running back Jeremiyah Love revealed why he is looking forward to this week's game against Fred Warner and ...