HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

Cataracts are the leading cause of blindness in adults older than age 50 worldwide.The global prevalence of cataracts has ...

Sutureless amniotic membrane (ProKera) was found to be partially or completely effective in corneal healing or symptomatic relief in just under two thirds of the eyes in our series. In our study ...

Surgeons restored corneal surfaces in the injured eyes of 14 patients in a small clinical trial. Stem cells from each patient’s healthy eye were cultivated in a lab to grow healthy tissue that could ...

Eye injuries that damage the cornea are usually irreversible and cause blindness. But a new clinical trial has repaired this damage in patients thanks to a transplant of stem cells from their ...

When a person's cornea is damaged, the injury can deplete the limbal epithelial cells. As a result, the surface of the eye develops permanent damage -- a condition called limbal stem cell deficiency.

The study uncovers the molecular 'rules' driving the arrangement of emerin into nanoclusters and the mechanisms leading to their defective assembly in people with muscular dystrophy. A new ...

Novel stem cell therapy repairs 'irreversible' corneal damage in clinical trial Date: March 4, 2025 Source: Mass Eye and Ear Summary: Results from a phase 1/2 clinical trial of a novel stem cell ...

A new stem cell therapy has repaired blinding damage to the cornea in 93% of patients in an early clinical trial. However, severe injuries, such as those caused by chemical burns or infections ...

using only donor Descemet's membrane with endothelium. However, early adoption by corneal surgeons has been limited (illustrated by graft registry reports: 0.7% all corneal transplants in the USA; 0.4 ...

Duchenne muscular dystrophy causes progressive muscle degeneration and weakness, but physical exercise should still be part of a comprehensive treatment strategy. Duchenne muscular dystrophy (DMD ...

Results also showed significant improvements in corneal staining and tear production, with effects observed as early as week 4 and maintained through week 12. Patients reported reduced reliance on ...