The team's approach uses AFM in several advanced modes—including Kelvin probe force microscopy and photoinduced force microscopy. These methods measure changes in surface potential, stiffness ...

Living Cell Study at the Single-molecule and Single-cell Levels by Atomic Force Microscopy Xiaoli Shi; Xuejie Zhang; Tie Xia; Xiaohong Fang Disclosures Nanomedicine. 2012;7 (10):1625-1637.

Atomic force microscopy (AFM) is a technique originally developed to assess the physical and mechanical properties of materials at extremely high resolutions, but the imaging speeds aren't fast ...

Table 1. Living-cell atomic force microscopy study of clinical drugs and patient samples. Disease/cell type Drug AFM method Content Ref. HaCaT keratinocytes Glyphosate Imaging, elasticity Studied ...

Taking advantage of decades of AFM innovation, Dimension Nexus delivers exceptional value. Its open-architecture system with low drift and low noise enables researchers to collect high-quality data ...

Neurological disorders are becoming an increasingly significant societal burden, highlighting the critical need for improved ...

Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43347-3 The transport of ions to and from a cell is controlled by pore-forming proteins embedded in the cell membrane.

A twisted cell-cell adhesion molecule complex structure revealed by single-molecule fluorescence microscopy and high-speed atomic force microscopy ...

The study of biological systems varies from whole organisms, organs, and organoids, down to their building blocks of proteins and cells. At the lower end of the scale, atomic force microscope (AFM) ...

By utilizing atomic force microscopy (AFM) combined with finite element computer simulations, they were able to show that cell stiffness is very sensitive to internal turgor pressure.

Ayoub Glia, Muhammedin Deliorman, Mohammad A. Qasaimeh. 3D Generation of Multipurpose Atomic Force Microscopy Tips. Advanced Science, 2022; 2201489 DOI: 10.1002/advs.202201489 ...

Technology advances have steadily been implemented to improve the performance of commercial atomic force microscopes (AFMs) since the release of the first commercial model about 30 years ago. Now, the ...