The NFC South takes center stage this week as the 4-9 Atlanta Falcons head to Florida to face the 7-6 Tampa Bay Buccaneers in a matchup with major divisional implications.

Christian McCaffrey will lead the San Francisco 49ers (9-4) into their matchup against the Tennessee Titans (2-11) at Levi's Stadium on Sunday at 4:25 p.m. ET.