Ocular manifestations like xanthelasma and arcus corneae are early indicators of high cholesterol and increased ...

You can activate the macrophage and make the muscle twitch subtly almost immediately," Jankowski says. Meanwhile, the connected macrophages triggered a similar process of cell regeneration that helped ...

Trained immunity is reshaping our understanding of host defense by demonstrating that innate immune cells once thought to lack memory can be reprogrammed to mount heightened responses to subsequent ...

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Background: Functional HDL exhibiting antioxidant and anti-inflammatory properties and supports cardiovascular health by regulating cellular cholesterol. Oxidative stress impairs HDL function, leading ...

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses. A deficiency in the oxygen-carrying capacity ...

Fighting off pathogens is a tour de force that must happen with speed and precision. A team of researchers at CeMM and MedUni Vienna led by Christoph Bock and Matthias Farlik has investigated how ...

Department of Cardiology, The First People’s Hospital of Baiyin, Baiyin, Gansu, China Members of the interleukin-1 (IL-1) superfamily play crucial roles in orchestrating inflammation and immune ...

Atherosclerosis, which is defined by plaque accumulation within artery walls, is one of the leading causes of cardiovascular disease and mortality. Although they help control symptoms and slow the ...

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

The star of Monday’s deal is gusacitinib, a small-molecule drug that Formation is developing for chronic hand eczema. Sanofi will explore additional indications for gusacitinib in a Phase I study.

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...