The San Francisco 49ers may have to alter course on their plan to play starters in the preseason vs. the Las Vegas Raiders.

There are a slew of players suiting up for the 49ers against the Las Vegas Raiders on Saturday who are almost certainly not going to make the 53-man roster. That turns our attention to the rookie ...

The San Francisco 49ers will need to trim down their roster from 90 players to 53 soon, and they may try to get something back in a trade.

The San Francisco 49ers already lean heavily on two seventh-round picks, now they may have another in their starting lineup.

The San Francisco 49ers are bringing back an old friend, as they've signed Malik Turner for a third time in four years.

San Francisco 49ers wide receiver Ricky Pearsall wants to be on the same page as his quarterback after missed time together last year and in camp.

Head coach Kyle Shanahan on Monday after the 49ers' practice told reporters in a press conference that Aiyuk could return by ...

The San Francisco 49ers couldn't get through their joint practice with the Las Vegas Raiders without an injury scare.

The San Francisco 49ers rookies had up-and-down performances against the Denver Broncos in Week 1 of the NFL preseason.

The San Francisco 49ers' brutal injury luck continues, as they've now lost offensive tackle Andre Dillard for the year.

To make room on the 90-man roster the 49ers waived quarterback Tanner Mordecai and placed veteran running back Ameer Abdullah ...

The 49ers opened their preseason with a 30-9 loss against the Denver Broncos from Levi's Stadium in Santa Clara, Calif. While ...