Arizona Cardinals running back James Conner has been ruled out of Sunday's game against the San Francisco 49ers due to a knee injury, coach Jonathan Gannon said Wednesday. Conner, 29,

Running back Michael Carter was signed from the practice squad, joining DeeJay Dallas, to make it two runners on the active roster. Tony Jones Jr. is a candidate to be elevated from the practice squad for Sunday’s game. Hassan Hall was signed to the practice squad Tuesday.

Conner exited last Sunday's loss to the Carolina Panthers, which officially ended Arizona's playoff dreams, after suffering the injury in the third quarter. The offense sorely missed his production in the second half and overtime period. Kyler Murray and company hope he is able to return to the backfield for the final stretch of the season.

Cardinals running back James Conner suffered a knee injury in Sunday's loss to the Panthers and did not return. Will he play against the Rams?

SOFI STADIUM -- Arizona Cardinals RB James Conner is questionable to return to Week 17's battle against the Los Angeles Rams with a knee injury. Conner was questionable with a knee injury heading into Saturday after being a limited participant on all three days - he initially suffered the injury in last week's loss against the Carolina Panthers.

James Conner will not play in the Arizona Cardinals ’ season finale against the San Francisco 49ers, coach Jonathan Gannon said Wednesday.

Conner initially suffered a right knee injury on a tackle in the third quarter of the Cardinals’ Week 16 loss to the Panthers. He did not return to the game but after three limi

ARIZONA -- The Arizona Cardinals again saw running back James Conner on the practice field ahead of their Week 17 prep against the Los Angeles Rams, potentially giving a good sign for his status moving into the weekend.