This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of ...

State-of-the-art technology could accelerate novel drug development, advance precision medicine Intellicule founders Purdue ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

Intellicule has received a $217,941 NIH SBIR Phase I grant to develop advanced deep-learning software for biomolecular ...

Swedish Orphan Biovitrum AB (STO: SOBI) recently announced that it has entered into an acquisition agreement with Arthrosi ...

Intellicule, a software company whose solutions determine the 3D structures of biomolecules imaged with cryogenic-electron microscopy (cryo-EM), has received a $217,941 Small Business Innovation ...

Using cryo-electron microscopy, researchers have visualized how widely used epilepsy drugs bind and reshape the neuronal ...

Cryo-EM revealed HIV-1 integrase’s distinct structures as it shifts between its two roles of DNA integration and RNA-binding.

Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

Researchers have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...