Proteolytic degradation products of fibrinogen, produced as a result of excessive fibrinolysis, have been demonstrated in the blood of cirrhotic patients. 7,8 Such degradation products, when formed in ...

The first study to examine the effects of whole-chocolate consumption on ex vivo platelet function has shown that dark chocolate acutely reduces collagen-stimulated platelet aggregation and reduces ...

Platelets are expert at patching up leaks in blood vessels, but could they go overboard and seed amyloid-β plaques as well? As reported in Science Signaling on May 24, Aβ monomers bind integrin ...

Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity. In this study, we further evaluated the antiplatelet ...

When cancer cells and platelets mix, the risk of metastasis and cancer-related deep vein thrombosis (DVT) and pulmonary embolism (PE) increases, but a small, proof-of-concept study suggests that the ...

Bleeding because of impaired platelet function is a major side effect of the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib. We quantitatively assessed ristocetin-induced platelet aggregation ...

Abnormalities of platelet function in some patients with primary, but sporadic, disorders of hemostasis have been attributed to impaired release of platelet adenosine diphosphate (ADP). This defect ...

Assessment of feasibility and willingness of former heavy smokers to participate in chemoprevention trials to prevent lung cancer. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I.

Moderate alcohol consumption is believed to reduce mortality from cardiovascular disease. Binge drinking, on the other hand, is known to increase mortality from all causes. Recent findings indicate ...

Thrombocytopenia (low platelet count) is common in people with cirrhosis. Possible causes include an enlarged spleen and decreased platelet production. Severe thrombocytopenia can increase the risk of ...

Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels. Cardiologists have long known that platelets can become "hyperreactive" to cause ...