Diabetic nephropathy (DN), characterized by progressive damage to the glomeruli and tubulointerstitial compartments, is driven by metabolic reprogramming and mitochondrial dysfunction, including ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

Many of us remember from high school biology class that mitochondria are the cell’s “power plants.” These small kidney-bean-shaped structures are what convert nutrients from food into ATP — the cell’s ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare. Patients ...