This review focuses on the vital interconnections among lysosomes, iron metabolism, and mitochondria in osteoclasts.

Protein, but not mRNA, levels of neurodegenerative disease-associated protein TDP-43 are decreased upon knockdown of BORC, a complex that is required for the anterograde transport of lysosomes.

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures.

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in ...

Inherited metabolic diseases are rare monogenic conditions that disrupt biochemical pathways, affecting energy production and ...

A new discovery inside your cells may change how scientists understand disease and design future treatments. Researchers have found a previously unknown structure in mammalian cells, something they ...

Coccolithophores are a type of single-celled microalgae that fix CO2 into organic matter and precipitate calcium carbonate, ...

The protein homeostasis (proteostasis) network (Balch et al, 2008), consisting of a collection of molecular chaperones, ...

The Greater Bengaluru Governance Act, 2024, that has already come into effect is gradually being implemented. While the Greater Bengaluru Authority (GBA) has already been constituted, the last step - ...