Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

This study reveals how gene expression patterns uncover molecular pathways linking comorbidities, enhancing treatment strategies for overlapping diseases.

While the process via which different types of neurons are produced, also known as neurogenesis, has been the focus of numerous neuroscience studies, its genetic and biological underpinnings in humans ...

How rapidly gene expression in a single cell changes over time can provide insight into how cells might become more specialized. A new method to calculate RNA velocity, developed by researchers at ...

How do cells know what they should become as the body develops? Biological development depends crucially on spatial patterns: ...

Brian Cunniff, an assistant professor of pathology and laboratory medicine at the University of Vermont, will discuss how the subcellular positioning of mitochondria regulates gene-expression patterns ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Populations live in rapidly changing environments—droughts come and go, food sources change, human activities reshape ...

Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better drugs for this psychiatric disorder. To test this hypothesis, Girgenti and his ...

Researchers led by Dubravka Vučićević at the Max Delbrück Center have developed a new method to discover how DNA controls genes. Their technique, published in “Cell Genomics,” can reveal the genetic ...