This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of ...

State-of-the-art technology could accelerate novel drug development, advance precision medicine Intellicule founders Purdue ...

Intellicule, a software company whose solutions determine the 3D structures of biomolecules imaged with cryogenic-electron microscopy (cryo-EM), has received a $217,941 Small Business Innovation ...

A new study explains how cholesterol-lowering medications can lead to muscle damage and identifies a possible approach to making these treatments safer. Statins have dramatically improved cardiovascul ...

Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Intellicule has received a $217,941 NIH SBIR Phase I grant to develop advanced deep-learning software for biomolecular ...

Researchers have characterised the structure and function of a key protein that helps breast cancer cells survive.

Researchers at LMU have uncovered how ribosomes, the cell’s protein builders, also act as early warning sensors when ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.