Other studies in culture have implicated Dgs in basement membrane assembly 6, 7, 8 as well as in agrin-induced aggregation of AChRs in myotubes 3, 4.

Background/Aims To investigate the efficacy of therapeutic soft contact lenses (SCLs) in gelatinous drop-like corneal dystrophy (GDLD) management. Methods This was a retrospective, consecutive, ...

Results: 20 eyes of 20 patients with RCE caused by trauma (n = 14), anterior basement membrane dystrophy (n = 5) or idiopathic (1) were studied. The mean age of patients was 44 years and mean ...

Background Idiopathic pulmonary fibrosis (IPF) is characterised by damage to the epithelial layer, closely associated with the alveolar basement membrane (BM). We aimed to investigate how type IV ...

By MATTHEW PERRONE, Associated Press WASHINGTON (AP) — Shares of Sarepta Therapeutics plunged Monday after the biotech drugmaker reported a second death in connection with its gene therapy for ...

Clinical outcome was evaluated as defined by Maharajan et al. [23] The objective of the ProKera was one or more of the following: to promote epithelialization, to prevent corneal perforation, to ...

GenEditBio Limited has announced the first patient has been dosed in an investigator-initiated trial (IIT) of GEB-101, an in vivo genome editing program for TGFBI corneal dystrophy. TGFBI corneal ...