Ibuprofen might have advantages over indomethacin, when used to effectuate closure of a neonate's patent ductus arteriosus (PDA). Several previous studies indicate that platelet plug formation is ...

Dr. Woulfe's research interests focus primarily on the intracellular signaling mechanisms of platelet activation and how signaling in platelets contributes to thrombosis in vivo. Agonists that extend ...

Platelets are the smallest of the human blood cells, measuring about one-tenth the diameter of a white blood cell. They usually circulate freely, maintained in a mobile but inactive state by molecules ...

When the body experiences an injury to a blood vessel, muscular response to the injury causes the vessel to constrict, decreasing blood flow to the area. The blood is exposed to collagen in the ...

PHILADELPHIA — Blood platelets shore up open wounds and help cuts heal, but they can also cause heart attacks and strokes when a congealed ball of platelets known as a thrombus breaks free from a site ...