The Tennessee Titans and Indianapolis Colts play on Sunday, Oct. 26, 2025 at Lucas Oil Stadium. The Titans are 1-6 and the Colts are 6-1.

USA Today's NFL experts make their picks for a Week 8 showdown between the Indianapolis Colts and Tennessee Titans

The Tennessee Titans (1-6) are back on the road this Sunday when they face the Indianapolis Colts (6-1) at Lucas Oil Stadium in Indianapolis, Indiana, at 3:25 p.m. CDT. Opening the week, the Titans were listed as 14-point underdogs, and as of this writing, that is where the spread currently sits.

After soundly defeating the Tennessee Titans in Week 3, the Indianapolis Colts are brimming with confidence to repeat.

Tennessee Titans quarterback Cam Ward flipped the script on the media during his Wednesday press conference. While it is typically the media asking the rookie signal-caller questions in such a situation, Ward put the spotlight back on them when he asked if they could recite a play call back to him after he read it.

The Tennessee Titans have a tough matchup with the Indianapolis Colts this week, and here are five matchups that could determine the outcome.

The Tennessee Titans have endured a number of season-altering issues throughout the 2025-26 season, not the least of which being consistent, nagging injuries on