This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of ...

A new study explains how cholesterol-lowering medications can lead to muscle damage and identifies a possible approach to making these treatments safer. Statins have dramatically improved cardiovascul ...

State-of-the-art technology could accelerate novel drug development, advance precision medicine Intellicule founders Purdue ...

Cryo-EM revealed HIV-1 integrase’s distinct structures as it shifts between its two roles of DNA integration and RNA-binding.

Intellicule has received a $217,941 NIH SBIR Phase I grant to develop advanced deep-learning software for biomolecular ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

Thermo Fisher Scientific is introducing a new, high-powered microscope aimed specifically at speeding up drug discovery research, with automated features that can help gather images at near-atomic ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Using cryo-electron microscopy, researchers have visualized how widely used epilepsy drugs bind and reshape the neuronal ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...