Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the ...
Figure 1: Skin carcinogenesis in wild-type and TNF-α –/– mice. TNF-α is a pleiotropic cytokine that could influence cells in both the epidermis and dermis, and early and late stages of tumor ...