Background: Thrombolysis for acute ischemic stroke has remained controversial. The Canadian Alteplase for Stroke Effectiveness Study, a national prospective cohort study, was conducted to assess the ...
WASHINGTON, DC—In PEERLESS, the first randomized controlled trial pitting two different interventional strategies against each other in pulmonary embolism (PE), patients with acute intermediate-risk ...
Background: Thrombolysis for acute stroke is beneficial in selected patients. Because clinical trials generally exclude patients with pre-existing disability, this subgroup of patients has not been ...
HELSINKI, Finland—Adding IV tirofiban improves functional outcomes among patients undergoing systemic thrombolysis for acute ischemic stroke within 4.5 hours of symptom onset, results from the ...
Intravenous thrombolysis with recombinant tissue plasminogen activator (IV rtPA) is an established and effective treatment for acute ischaemic stroke. 1,2,3 tPA is a serine protease that catalyses the ...
Fourteen randomised controlled trials (RCTs) comparing thrombolytic drugs were included in the review. Overall the studies were considered to be of excellent quality. In total, the trials involved ...
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