Newly discovered enzymes that are vital for bacterial defenses can also help chemists characterize the stereochemistry in natural products. The enzymes cut proteins between unusual amino acids, ...

We applied the SOSICS approach to generate a panel of stereochemically pure oligonucleotide components of mipomersen (Fig. 1c) to test the impact of stereochemistry on pharmacological parameters.

Automated reaction path search method predicts accurate stereochemistry of pericyclic reactions using only target molecule structure. Automated reaction path search method predicts accurate ...

When chemists at the University of Bristol set out to make a pair of natural products with antimicrobial activity, it seemed like a quick and easy way to highlight some synthetic methodology their lab ...