A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis — the process of cell death that is usually caused by infections and results in ...

Research in neuroinflammation has increasingly highlighted the role of non-neuronal cells, such as microglia, astrocytes, oligodendrocytes, endothelial ...

Pyroptosis is a proinflammatory type of cell death that is associated with gasdermin-mediated membrane hole formation, as well as cell enlargement and lysis. Pyroptosis plays an important role in both ...

Molecular mechanism by which Yersinia escapes RIPK1-mediated pyroptosis by interfering with host cell glucose homeostasis to activate AMPK. Credit: Xu Daichao According to a study published in Nature ...

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor ...

Robust pancreatic tumor suppression by a novel combination treatment with anti-PD-1 immune checkpoint antibody and stroma modifying RNA oligonucleotide STNM01 in mice. This is an ASCO Meeting Abstract ...

This schematic shows the cell death pathway called pyroptosis, Greek for going down in flames. When activated by a toxin or an infection, the enzyme caspase-1 initiates several reactions inside of the ...

A new study, published in Science, explores what happens in the body when bacteria like Yersinia and Salmonella are at peak activity. That could come in handy. Not only because Yersinia still exists ...

An “explosive” form of cell death, called pyroptosis, is part of the normal immune response to the toxins released by bacteria during an infection. But when the infection reaches the lungs, pyroptosis ...