PBC is a chronic liver disease that damages bile ducts and can lead to liver failure. You can get treatment for PBC to slow disease progression and manage symptoms like itching. There is no cure for ...

Cholangitis describes inflammation in the bile ducts or biliary system. Some forms of cholangitis can be life threatening. Treatment may involve antibiotics, drainage of the bile duct, and intravenous ...

Cholangitis and cholecystitis are two conditions that share some similarities but have different causes and symptoms. Cholangitis affects the bile ducts, while cholecystitis affects the gallbladder.

In patients with primary sclerosing cholangitis, biliary tract cancer is the leading cause of death. Yet very little is known about effective systemic treatments in these individuals. A new study ...

Acute cholangitis is a severe, bacterial infection of the biliary tract precipitated by an obstruction that often results in systemic inflammation and, in some cases, life‐threatening sepsis. This ...

Elafibranor, a dual peroxisome proliferator-activated receptor (PPAR) alpha and delta agonist, appears to be a safe and effective treatment of primary biliary cholangitis, according to a new clinical ...

—A large international cohort study of patients with primary biliary cholangitis recently demonstrated that the most recent liver stiffness measurement is the single strongest, independent predictor ...

Treatment with liberixibat led to a statistically significant improvement in itch compared with placebo. Topline results were announced from a phase 3 trial evaluating linerixibat for the treatment of ...

A primary biliary cholangitis (PBC) diagnosis can be life-changing. For many, it’s an emotional journey filled with questions, uncertainties and a need to redefine what life looks like with a chronic ...

Intercept Pharmaceuticals has voluntarily withdrawn Ocaliva (obeticholic acid) for the treatment of primary biliary cholangitis (PBC) from the US market. The decision follows a request from the FDA.