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Oklahoma vs. Missouri prediction, pick, odds, spread: No. 8 Sooners host former Big 12 rival Tigers
Oklahoma and Missouri played almost annually for a century, but this is just the second meeting between the former Big 12 rivals since 2011. The Tigers took their debut SEC showdown last season in a 30-23 win in Columbia.
The No. 8 Oklahoma Sooners look to continue their winning ways as the No. 22 Missouri Tigers come to Norman on Saturday.
Sooners Wire on MSN
No. 8 Oklahoma uses big defensive day, big 2nd quarter, to beat Mizzou
Oklahoma scored 14 of its 17 points in the second quarter and its defense kept Missouri out of the end zone in Saturday's win over the Tigers.
Behind them, the next wave of contenders is fighting through traffic. Notre Dame's demolition of Syracuse and Oklahoma's suffocating defensive performance have both pushed those programs to the verge of locking down playoff spots.
Week 13 of the 2025 season saw several teams score big wins that solidified their chances of making the College Football Playoff, including the Miami Hurricanes and Oregon Ducks.