People with cystic fibrosis who have clinical evidence of lung disease are prescribed rhDNase as the first choice of mucoactive agent. Sticky mucus accumulates in the lungs in people with cystic ...
Carbocisteine and Hypertonic Saline Show No Benefit, But Linked to Harm in Acute Respiratory Failure
In patients with critical illness and acute respiratory failure, adding carbocisteine or hypertonic saline (HTS) to usual care did not shorten the duration of mechanical ventilation. The use of these ...
Mucoactive agents did little to stave off pulmonary exacerbations of non-cystic fibrosis bronchiectasis, the CLEAR trial showed. In the two-by-two factorial trial testing hypertonic saline and ...
Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant human deoxyribonuclease) for people with cystic fibrosis? Why this is important- People ...
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