Diabetic nephropathy (DN), characterized by progressive damage to the glomeruli and tubulointerstitial compartments, is driven by metabolic reprogramming and mitochondrial dysfunction, including ...

The central goal of research in the Mears Lab is to investigate proteins that regulate mitochondrial dynamics. Mitochondrial dynamics has recently come to the forefront as a therapeutic target in ...

“Brief P110 treatment during the acute time period after TBI permanently normalized mitochondrial fission / fusion and prevented subsequent harm to the brain, including oxidative damage, blood-brain ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

Many of us remember from high school biology class that mitochondria are the cell’s “power plants.” These small kidney-bean-shaped structures are what convert nutrients from food into ATP — the cell’s ...

Nearly every cell in your body depends on mitochondria to survive and function properly. Mitochondria earned the nickname “powerhouse of the cell” because they provide 90% of our bodies’ energy. Less ...