In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

A single microarray can provide information on the expression of tens of thousands of genes. The amount of information generated by a microarray-based experiment is sufficiently large that no single ...

Now that gene expression microarray experiments are routine, the challenge is to extract accurate intelligence from the data they produce. The problem isn’t inaccuracies in the analysis software or ...

Investigators have two important questions to consider when evaluating microarray expression data. First, they must ask whether the results are valid—in other words, accurate—for the particular ...

A new study by 64 renowned scientists may bring us one step closer to personalized medical treatment--that is, medical treatment tailored to each person's unique genetic make-up and medical condition.

The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

With high-dimensional data, variable-by-variable statistical testing is often used to select variables whose behavior differs across conditions. Such an approach requires adjustment for multiple ...

KFB - Center of Excellence for Fluorescent Bioanalysis integrates Genomatix GeneChip® Analysis-Pipeline into its product portfolio. Premium services offered for premium results Munich, Regensburg ...

To determine whether increased androgen receptor protein concentration has a causal role in the hormone sensitive-to-hormone refractory transition, we introduced epitope-tagged wild-type AR cDNA, by ...

Collaboration between modellers and experimentalists is essential in ecological research, however, different obstacles linking both camps often hinder scientific progress. In this commentary, we ...