Melanocytes describe a specialized type of cell that generates a substance called melanin, a pigment responsible for skin and eye color. When several melanocytes cluster together, they form a benign, ...

Dysplastic nevi are benign melanocytic tumors containing clonal populations of hyperproliferative melanocytes. Strictly speaking, dysplastic nevus is a histologic diagnosis, characterized by ...

Please provide your email address to receive an email when new articles are posted on . Brain and/or spinal MRI were effective in detecting melanin in the central nervous system of children with ...

The first description of a particular melanocytic nevus found in relatives from six cases of melanoma was made in 1978. [1] Although initially coined B-K moles, these moles soon acquired the name ...

The dysplastic nevus initially was described in the 1980s as a mole with increased risk of developing melanoma and requiring total removal. However, dermatopathologists now consider dysplastic nevi to ...

RAS proteins are critical for cell divisions, differentiation, and apoptotic processes. Oncogenic RAS variations cause cancer, but they can also induce benign lesions such as thyroid nodules, colonic ...

Melanocytes arise from neural crest cells and populate the epidermis through migration. In all dermal melanocytosis subtypes, melanocyte migration is believed to be arrested in the dermis, leading to ...

The term "epidermal nevus syndrome" (ENS) is used for any of the various clinical entities which are distinctive in terms of their signs and symptoms, histopathology, and genetic composition. In most ...