RAS proteins are critical for cell divisions, differentiation, and apoptotic processes. Oncogenic RAS variations cause cancer, but they can also induce benign lesions such as thyroid nodules, colonic ...

Melanocytes describe a specialized type of cell that generates a substance called melanin, a pigment responsible for skin and eye color. When several melanocytes cluster together, they form a benign, ...

The first description of a particular melanocytic nevus found in relatives from six cases of melanoma was made in 1978. [1] Although initially coined B-K moles, these moles soon acquired the name ...

Please provide your email address to receive an email when new articles are posted on . Brain and/or spinal MRI were effective in detecting melanin in the central nervous system of children with ...

The dysplastic nevus initially was described in the 1980s as a mole with increased risk of developing melanoma and requiring total removal. However, dermatopathologists now consider dysplastic nevi to ...

Please provide your email address to receive an email when new articles are posted on . Melanocytic lesions in the lower extremities that are marked by peripheral globules should be closely watched ...

De-Escalation Strategies With Immune Checkpoint Blockers in Non–Small Cell Lung Cancer: Do We Already Have Enough Evidence?

Mathematical modeling of routine biological parameters kinetics in order to predict durable benefit for first-line immunotherapy in metastatic or unresectable melanoma.

Nevus of Ota, or nevus fuscoceruleus ophthalmomaxillaris, is a dermal melanocytic hamartoma that presents as bluish hyperpigmentation along the first or second branches of the trigeminal nerve.

The histology of our second case revealed dysplastic nevus with severe atypia. The presence of nevus cells on the lateral margin of a dysplastic nevus with severe dysplasia requires wider excision. In ...