Melanocytic nevi are a category of benign melanocytic proliferations with a number of subtypes. These include congenital melanocytic nevi, blue nevi, acquired melanocytic nevi, and Spitz nevi. Many of ...

Melanocytes describe a specialized type of cell that generates a substance called melanin, a pigment responsible for skin and eye color. When several melanocytes cluster together, they form a benign, ...

Allogeneic hematopoietic stem cell transplantation (HSCT) can provide curative therapy for children with life-threatening malignant and nonmalignant conditions. As long-term survival improves, ...

Please provide your email address to receive an email when new articles are posted on . Dermatologists should avoid the removal of benign nevi from children that are not of a consenting age, ...

Congenital melanocytic nevi (CMN) represent benign proliferations of melanocytes present from birth, varying considerably in size, morphology and distribution. In some instances, particularly when ...

Please provide your email address to receive an email when new articles are posted on . Brain and/or spinal MRI were effective in detecting melanin in the central nervous system of children with ...

A 4-week-old newborn presents confluent blue/gray patches across the buttocks, left leg, and chest and several vascular patches on her back and right thigh. What is her diagnosis? An otherwise healthy ...

RAS proteins are critical for cell divisions, differentiation, and apoptotic processes. Oncogenic RAS variations cause cancer, but they can also induce benign lesions such as thyroid nodules, colonic ...

Philadelphia, September 30, 2019 - Melanoma is the least common but one of the most deadly skin cancers. It accounts for only about one percent of all cases globally, but the majority of skin cancer ...

Dysplastic nevi are benign melanocytic tumors containing clonal populations of hyperproliferative melanocytes. Strictly speaking, dysplastic nevus is a histologic diagnosis, characterized by ...

The polyclonality of BRAF mutations in melanocytic nevi suggests that mutation of BRAF may not be an initial event in melanocyte transformation, according to a new report. The polyclonality of BRAF ...

The dysplastic nevus initially was described in the 1980s as a mole with increased risk of developing melanoma and requiring total removal. However, dermatopathologists now consider dysplastic nevi to ...