Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases' ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an ...

Organelle remodeling is critical for cellular homeostasis, but host factors that control organelle function during microbial infection remain largely uncharacterized. Here, a genome-scale CRISPR/Cas9 ...

Salmonella enterica is an intracellular bacterial pathogen that replicates within membrane-bound vacuoles through the action of effector proteins translocated into host cells. Salmonella vacuoles have ...