Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Understanding how living cells grow, respond to stimuli, and change over time is central to modern cell biology and drug discovery. Many traditional imaging approaches rely on fluorescent labels, ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...

Figure | Working principle of Interferometric Image Scanning Microscopy (iISM). (a) Schematic of the iISM microscope and interferometric PSF detection. (b) iISM with adaptive pixel-reassignment (APR) ...

Researchers at The Hong Kong University of Science and Technology (HKUST) have uncovered how mutations in a specific gene can trigger a rare respiratory disease, shedding light on the critical role ...

Using patient-derived cells and advanced imaging, researchers showed that RPGR mutations disrupt cilia coordination and ...

A robust, image-based neurotoxicity assay helps scientists streamline subcellular neuronal analysis with live-cell dyes and high-throughput automated microscopy. Neuronal cell culture models allow ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Laser-driven thermoviscous flows provide contact-free rotation, transport or stabilization of delicate samples such as ...

Peking University, Aug 18, 2025: Professor Xi Peng’s team from the College of Future Technology at Peking University has recently developed a triangle structured illumination microscopy (SIM), which ...