The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these potential risks. Now, ...

Certain cells, commonly called excitable cells, are unique because of their ability to generate electrical signals. Although several types of excitable cells exist — including neurons, muscle cells, ...

The transient receptor potential (TRP) ion channels comprise a diverse superfamily of cation channels that play pivotal roles in sensory transduction, enabling organisms to detect a wide range of ...

After the onset of painful peripheral stimuli, nociceptive neurons are activated and instigate a cascade of neuronal firings that transmit along the axons of the primary afferent fibers toward nerve ...

Two California-based scientists won the 2021 Nobel Prize in medicine or physiology on Monday for their discoveries of receptors for heat, cold, and touch. David Julius of the University of California, ...

This is a 3-D computer model of the serotonin 5-HT3 receptor, embedded through a lipid bilayer membrane (horizontal structure with black lines and yellow balls) as it would be naturally in a cell.

BUFFALO, N.Y. – The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these ...