A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Researchers have used an experimental mRNA therapy to make old immune cells in mice behave as if they were young again, reversing key signs of immune aging in a way that standard vaccines or drugs ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

Since addressing the COVID-19 pandemic, mRNA vaccines have risen as a promising tool for treating a broad range of diseases, such as cancer and genetic disorders. To be effective, foreign mRNA in ...

The administration had cut crucial funding for mRNA-based therapies. The rest of the world might step in and benefit.

Researchers from the University of Cologne and the Max Planck Institute of Biochemistry show that the targeted interaction of two proteins ensures that a key control mechanism in the formation of ...

Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...

The same groundbreaking technology that enabled rapid COVID-19 vaccine development is now poised to revolutionize medicine in ways that seemed impossible just a few years ago. Messenger RNA vaccines ...

Few medical advances in recent memory have sparked as much controversy as COVID-19 vaccines utilizing mRNA (messenger RNA). Currently, there are two such vaccines, from Pfizer-BioNTech and Moderna.