Upon evaluation of previous case reports, it is evident that careful consideration should be taken upon prescribing and monitoring topiramate therapy. Practitioners should obtain a detailed history ...

Your anion gap is more than just a lab number—it’s a window into your body’s acid–base balance and overall metabolic health. Understanding how it’s calculated, what’s normal for your lab, and how to ...

A Japanese registry has identified a blind spot in the routine care of patients with chronic kidney disease (CKD). Serum bicarbonate levels are rarely measured, leaving metabolic acidosis largely ...

Acid-base disorders are frequent in emergency and critical care, but many patients present with more than one imbalance at once. Clinicians rely on structured methods like anion gap correction and ...

Credit: Thinkstock Sodium bicarbonate is the most common treatment, but it has notable limitations, particularly in terms of patient adherence. Sodium bicarbonate has some down sides, but there are ...

Background: In vitro data suggest that lower extracellular pH activates the immune system. We conducted a population-based study of the relation between serum acid–base status and inflammation.