The majority of drug interactions today are attributed to the cytochrome P450 (CYP450) isoenzyme system. However, new data suggest that transport proteins also play a key role. One such transporter is ...

Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), uses its spike (S) glycoprotein to enter host cells. The S glycoprotein consists of ...

3D structural findings are reported on a critical component of the Nipah virus' infection mechanism, and how antibodies home in on an important part of the machinery that attaches the virus to host ...

Stanniocalcin-1 (STC1) is a glycoprotein hormone involved in calcium/phosphate homeostasis, which regulates various cellular processes in normal development and tumorigenesis. After analyzing more ...

Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, influencing their stability, bioactivity, and immunogenicity. Glycoprotein characterization and glycosylation profiling ...

Astellas has become the latest big pharma company to sink some money into immuno-oncology start-up GO Therapeutics, forging an alliance to develop antibodies targeting two glycoprotein targets. The ...

The lack of high-resolution structures of the hantavirus glycoprotein tetramer and its lattice organization has limited mechanistic insights into viral assembly and entry. The authors leveraged a ...

Replacing a step in sample preparation with an automated approach improves both method precision and productivity. Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, ...