The effects of disease-associated genetic variants on gene expression and genome accessibility have been analysed together.

AI-designed proteins improved targeted DNA insertion in cultured cells, with one variant doubling the performance of an ...

The DNA in our cells wraps around proteins called histones to form nucleosomes, which organize into chromatin. This ...

Gene-editing techniques could soon allow researchers to replace entire genes and engineer complex cellular circuits — if the ...

(Agnes Noy/Catley et al., Nucleic Acids Research, 2026) If you could peer inside a cell's nucleus, you would find DNA tightly ...

Learn how a sample from the tortoise Jonathan’s mouth revealed youthful patterns in his gene regulators that may help explain ...