The other examples of aromatic and aliphatic C–H oxidation reactions proceeding through ‘oxidation-first’ mechanisms mentioned above function because the high-valent intermediate provides access to a ...

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple ...

Scientists generalize the synthesis of aminating agents to simplify the design and manufacture of drugs and other fine chemicals in which nitrogen atoms play key roles. Each of these agents contains ...

Recent studies show that redox-active small molecules are selectively cytotoxic to chronic lymphocytic leukemia (CLL). Although elevated levels of reactive oxygen species in CLL cells have been ...