Giant migrating contractions (GMCs) are powerful waves of colonic movement that propel intestinal contents toward the anus and are essential for defecation. Yet despite their physiological importance, ...

A team co-led by a City University of Hong Kong (CityU) neuroscientist has identified a key mechanism of a biological clock that ensures roundworms stay regular by defecating at steady intervals. The ...

A randomized, double-blind trial found that adults with mild constipation who drank a vinegar beverage daily for four weeks ...

P2X7 Receptor–Mediated Colonic Motility Mechanism Driving Defecation-Inducing Strong Contractions by ATP (IMAGE) Saitama University ...