A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...
Zhi “Zack” Zheng is a member of molecular biologist Scott Keeney's lab. Zhi “Zack” Zheng, who is scheduled to receive his PhD from the Gerstner Sloan Kettering Graduate School of Biomedical Sciences ...
Efficacy and safety data from Ph1b, dose optimization trial of two doses of TH1902 (sudocetaxel zendusortide), a novel SORT1-targeting peptide drug conjugate (PDC), administered weekly vs q3weekly in ...
BRCA1 and BRCA2 genes play a crucial role in repairing damaged DNA. Mutations in BRCA1 and BRCA2 substantially increase the likelihood of breast and ovarian cancer, respectively. This new research ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
The human repairome, REPAIRome, will allow researchers around the world to rapidly check out how each of the 20,000 human genes affects DNA repair You can always be judged by your scars. This is the ...
A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.
Broken String Biosciences launched an early access program (EAP) through which select developers of gene edited therapeutics will be able to use Broken String’s INDUCE-seq ® technology in their own ...