MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...

The University of Colorado Boulder Biochemistry Department's Krios Electron Microscopy facility (BioKEM) offers single particle cryo-EM and cryo tomography of plunge-frozen samples. The BioKEM ...

Here, cryo-electron tomography (cryo-ET) of PRC1–chromatin condensates reveal randomly oriented neighboring nucleosomes in a stable, open chromatin mesh that might exclude large protein ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Deciphering the structures of proteins is critical to structural drug design. Cryo-electron microscopy (cryo-EM) now offers a radically different way to study the structure of large biomolecules ...