Successful microbial infection and host colonization depend on the ability of pathogens to evade, resist and/or manipulate host defenses. While much of our understanding of mechanisms underlying the ...

Viruses are masters at taking over our cells: They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes ...

Cancer cells need large amounts of energy to survive and multiply. To produce that energy, they rely on structures inside the cell called mitochondria, often described as the cell's "powerhouse." ...

Microscopy image of a human stem cell-derived hippocampal organoid. When the tissue carries an epilepsy-causing variant in the SCN8A gene, inhibitory neurons (seen in red) are disrupted, and ...

Summary: Researchers cracked open the earliest cellular origins of Rett syndrome. The investigation bypassed traditional tissue-level barriers by physically separating genetically healthy and mutated ...