Israel has severely weakened Hamas and Hezbollah. Now it's going after another member of Iran's so-called axis of resistance: the Houthi rebels of Yemen.

An American missile defense system was used for the first time to intercept a retaliatory attack launched by Yemen’s Houthis rebels at Israel’s central airport overnight as threats continue to escalate between the Jewish state and Iran’s terror proxies.

For the fifth night in the last eight days, sirens sounded in large swathes of central Israel overnight Thursday-Friday, after another ballistic missile attack by Yemen’s Houthis.The Iran-backed group took responsibility for the attack,

The Houthis have ramped up their attacks on Israel, while Israeli leader Benjamin Netanyahu says the fight against the militant group “is only getting started.”

An official says the Yemeni group will not stop until the war in Gaza ends, as Israel's PM says it is "just getting started".

The strikes come as Israelis endure continued rocket attacks from the Houthi militia in Yemen even as attacks from Hezbollah in Lebanon and Hamas in the Gaza Strip have diminished.

Israel launches waves of attacks across Yemen in retaliation for Houthi missile and drone strikes Israeli newspaper Haaretz reported that Israel Defense Forces warplanes hit Sanaa International Airport in the capital, which is controlled by the Houthis. Sources in Yemen also reported strikes on the port city of Hodeida.

As officials caution that ballistic missile and drone attacks from Yemen are likely to persist, Jerusalem is indicating that Thursday’s strikes are

Israel struck multiple targets in Yemen it said were controlled by Houthis, the last of the Iran-backed groups still fully engaged in the regional war that began 14 months ago.