Moore tells EW she previously interpreted the industry's treatment of her as a sign to leave acting behind: "Maybe the universe was saying that I was done."

Demi Moore may be a Hollywood staple, but her place in the upper echelon of critical success has remained shaky. That just changed.

The Substance took theaters by storm, but the body horror film starring Demi Moore is not for the weak. Some people might want to watch it at home so they can take a breath and a walk around the block whenever they need to get away from French filmmaker Coralie Fargeat’s confrontational and explicit imagery.