Mâcon, historically anglicised as Mascon, is a city in east-central France. It is the prefecture of the department of Saône-et-Loire in Bourgogne-F…Mâcon, historically anglicised as Mascon, is a city in east-central France. It is the prefecture of the department of Saône-et-Loire in Bourgogne-Franche-Comté. Mâcon is home to near 34,000 residents, who are referred to in French as Mâconnais. The city gave its name to the nearby vineyards and wine 'appellation'.